Average Dose: Men 50-100 mg/day
Active Life: 5-7 days
Ovinum / Clomid 10 x 50 mg $18.20
Advertisers of Clomid claim that it stimulates LH—and thus testosterone — production. But what makes Clomid effective is that it prevents estrogen from inhibiting the hypothalamus and pituitary, not by stimulating them.
Clomid is a mixed activator/blocker of estrogen. Attached to the estrogen receptor, it shapes it somewhat differently than estradiol does. The receptor must bind estrogen at its site and also bind any of certain cofactors at theirs.
The estrogen receptor is inactive unless the cofactor is bound. Each tissue uses a different cofactor. Some cofactors can bind to the estrogen receptor, but others are blocked by the altered shape. Clomid thus acts as an antagonist in some tissues (breast tissue, hypothalmus), and as an agonist in others (bone tissue). It also raises the blood cholesterol level.
Clomid/Ovinum in the Uk, Usa, Australia, Canada
Clomid can also reduce damage of muscles due to exercise. This is very important for athletes, but not very significant, if at all, with reasonable weight training. Clomid does not affect weight gains noticeably either way, in my experience.
Men generally find that 50-100 mg per day for 4-6 weeks restores testosterone production to normal. A very common dosage regimen is: 300 mg/day 1, 100 for 2-11, and 50 for 12-21.
This increase should come slowly but evenly during that period. Many want to see the raise immediately, so they prefer to combine Clomid with HCG for a week or two after the steroids are removed. The resulting kick-start also helps restore the testes normal ability to respond to endogenous LH, caused by prolonged inactivity.
Once off HCG, the user continues taking Clomid only. And as the hypothalmus may be inhibited by increased hormone levels, HCG should not be taken for more than two or three weeks. Remember, too, that injectable steroids can stay active for a long time and counter the effects of ancillary medications. So wait two to three weeks for androgen levels go down, preparing the body for normal testosterone production